National Institute Of Biological Sciences, Beijing;北京生命科學研究所
发明人:
ZHANG, Zhiyuan,WANG, Xiaodong,SU, Yaning,RUAN, Hanying,REN, Yan
申请号：
HK18104020
公开号：
HK1244792B
申请日:
2018.03.23
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
