National Institute of Biological Sciences; Beijing
发明人:
Zhiyuan Zhang,Xiaodong Wang,Shaoqiang Huang,Bo Yan,Lei Liu,Huayi Wang,Jianguang Han,Zhi Huang,Weiye Cao
申请号:
US16550316
公开号:
US20190381052A1
申请日:
2019.08.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides compounds that inhibit human MLKL, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.