Systems and methods for generating a processed fortified human milk product from raw human milk, and processed fortified human milk product compositions obtained thereby, are provided. The processed fortified human milk product composition possesses high nutritional content such as high concentrations of protein and human milk oligosaccharides. The processed fortified human milk product composition exhibits low overall bioburden and is non-allogenic and non-immunogenic. When ingested by an individual, the processed fortified human milk product composition achieves high bioavailability and reduces inflammatory processes.
