SOBCZYK, OLIVIA;SAM, KEVIN;MANDELL, DANIEL M.;CRAWLEY, ADRIAN P.;MIKULIS, DAVID;FISHER, JOSEPH;POUBLANC, JULIAN;DUFFIN, JAMES
发明人:
FISHER, JOSEPH,SOBCZYK, OLIVIA,CRAWLEY, ADRIAN P.,POUBLANC, JULIAN,SAM, KEVIN,MANDELL, DANIEL M.,MIKULIS, DAVID,DUFFIN, JAMES
申请号：
CA2946619
公开号：
CA2946619A1
申请日:
2015.04.27
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The interpretation and assessment of cerebrovascular reactivity (CVR) images relies on a qualitative review of possible abnormalities, which are viewed as inhomogeneities in the CVR maps that appear to differ from the CVR maps of healthy individuals. An imaging system which combines z-maps with a standardized stimulus offers a high resolution image indicating the presence, localization and severity of the pathological CVR. The standardized stimulus is in the form of targeted arterial partial pressures of carbon dioxide which allow one to assess the severity and distribution of an abnormality or reduction in a subject's vascular response to a vasoactive stimulus in at least one region of interest of the subject's brain. Z-maps have been found to be useful to reduce the effects of test- to- test, subject- to- subject and platform- to platform variability for comparison of CVR images.
