METHOD OF PRODUCING VIRUS-LIKE PARTICLES OF PICORNAVIRUS USING A SMALL-UBIQUITIN-RELATED MODIFIER FUSION PROTEIN EXPRESSION SYSTEM

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专利权人:

发明人:

Ting-Fang Wang,Shu-Mei Liang

申请号：

US14167243

公开号：

US20140178482A1

申请日:

2014.01.29

申请国别(地区):

US

年份:

2014

代理人:

摘要：

A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.

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