- 55 - NOVEL PEPTIDES FOR TREATING AND PREVENTTNG IMMUNE- RELATED DISORDERS, INCLUDING TREATING AND PREVENTING INFECTION BY MODULATING INNATE IMMUNITY ABSTRACT OF THE DISCLOSURE 5 [001441 IN ONE ASPECT. THE PRESENT INVENTION PROVIDES ISOLATED NOVEL PEPTIDES THAT CAN BE USED TO MODULATE INNATE IMMUNITY IN A SUBJECT. AND/OR FOR THE TREATMENT OF AN IMMUNE-RELATED DISORDER, INCLUDING TREATING AND PREVENTING INFECTION BY MODULATING INNATE IMMUNITY. ALSO PROVIDED ARE AN AGENT REACTIVE WITH THE PEPTIDE, A PHARMACEUTICAL COMPOSITION THAT INCLUDES THE PEPTIDE, AN ISOLATED NUCLEIC ACID I 0 MOLECULE ENCODING THE PEPTIDE, A RECOMBINANT NUCLEIC ACID CONSTRUCT THAT INCLUDES THE NUCLEIC ACID MOLECULE. AT LEAST ONE HOST CELL COMPRISING THE RECOMBINANT NUCLEIC ACID CONSTRUCT, AND A METHOD OF PRODUCING THE PEPTIDE USING THE HOST CELL. THE PRESENT INVENTION FURTHER PROVIDES A METHOD FOR TREATING AND/OR PREVENTING INFECTION IN A SUBJECT BY ADMINISTERING THE PEPTIDE OF THE INVENTION TO THE SUBJECT, 1 5 THEREBY MODULATING INNATE IMMUNITY IN THE SUBJECT. ADDITIONALLY, THE PRESENT INVENTION PROVIDES A METHOD FOR PREDICTING WHETHER A SUBJECT WOULD BE RESPONSIVE TO TREATMENT WITH A PEPTIDE OF THE INVENTION. FIG. 2E
