The invention discloses a composition comprising at least one long chain polyunsaturated fatty acid, at least one probiotic and a mixture of oligosaccharides, said mixture containing at least one N-acetylated oligosaccharide, at least one sialylated oligosaccharide and at least one neutral oligosaccharide, for use in brain growth and/or cognitive and/or psychomotor development. This composition is particularly adapted for use in infants, notably preterm infants.本發明揭示包含至少一種長鏈多不飽和脂肪酸、至少一種益生菌及寡糖混合物之組合物,該混合物含有至少一種N-乙醯基化寡糖、至少一種唾液酸基化寡糖及至少一種中性寡糖,該組合物用於腦成長及/或認知及/或心理動作發展。此組合物尤其適用於嬰兒、尤其早產嬰兒。