RAMESH, VENKAT MATUR,THIRUMENI, NAGARAJAN,RAJENDAR, BURKE,NARENDER, DEV MANTENA,MAHIMA, DATLA
申请号:
CA2989230
公开号:
CA2989230A1
申请日:
2016.06.21
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to a multivalent Pneumococcal conjugate vaccine (PCV) composition comprising: 1) at least 12 capsular polysaccharides selected from serotypes 1, 3, 4, 5, 6B, 7F, 9N, 9V, 15B, 14, 18C, 19A, 19F, 22F, 23F and 33F of S. pneumoniae activated with CDAP and conjugated to carrier protein selected from CRM197, pneumococcal surface protein A (PspA), pneumococcal adhesin protein (PsaA) or combination thereof and 2) a pharmaceutically acceptable carrier, wherein the composition does not contain capsular polysaccharide from serotype 6A.