Ramesh Venkat Matur,Nagarajan Thirumeni,Rajendar Burki,Narender Dev Mantena,Mahima Datla
申请号：
US15772771
公开号：
US20190240308A1
申请日:
2016.06.21
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a multivalent Pneumococcal conjugate vaccine (PCV) composition comprising: 1) at least 12 capsular polysaccharides selected from serotypes 1, 3, 4, 5, 6B, 7F, 9N, 9V, 15B, 14, 18C, 19A, 19F, 22F, 23F and 33F of S. pneumoniae activated with CDAP and conjugated to carrier protein selected from CRM197, pneumococcal surface protein A (PspA), pneumococcal adhesin protein (PsaA) or combination thereof and 2) a pharmaceutically acceptable carrier, wherein the composition does not contain capsular polysaccharide from serotype 6A.
