Indiana University Research and Technology Corporation
发明人:
Mervin Yoder,Nutan Prasain
申请号:
US15124280
公开号:
US20170022476A1
申请日:
2015.03.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates generally to methods and compositions useful in cell and tissue biology and therapeutics. In particular, an in vitro method for differentiating pluripotent cells into endothelial colony forming cell-like cells (ECFC-like cells) is provided. A purified human cell population of NRP-1+CD31+ ECFC-like cells is provided, wherein at least some of the cells in the population have a high proliferation potential. Therapeutic and test agent screening methods for using the cell populations of the present disclosure are provided.