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Palatable suspending vehicle for pharmaceutical ingredients
专利权人:
发明人:
Joshua Radke,Michael Jones,Martin Erickson
申请号:
US14034198
公开号:
US08986729B2
申请日:
2013.09.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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