A COMPOSITION FOR PREVENTION OF HAIR LOSS AND PROMOTION OF HAIR GROWTH COMPRISING EXTRACTS OF ECLIPTA PROSTRATA, FRACTIONS THEREOF, TERTHIENYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;한국생명공학연구원
发明人:
KIM, SEUNG HO,김승호,KIM, JAE WHA,김재화
申请号：
KR1020110119848
公开号：
KR1020120052894A
申请日:
2011.11.16
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition containing Eclipta prostrate extract, fraction thereof, terthienyl derivatives and pharmaceutically acceptable salt is provided to remarkably suppress TGF-beta expression and to promote hair growth. CONSTITUTION: A pharmaceutical composition for preventing alopecia or promoting hair growth contains Eclipta prostrate extract or fraction thereof as an active ingredient. The extract is prepared using water, low carbon number alcohol of C1-4, or mixture thereof. A cosmetic composition for preventing alopecia or promoting hair growth contains the extract or fraction thereof as an active ingredient. The pharmaceutical composition contains terthienyl derivative of chemical formula 1 or pharmaceutically acceptable salt thereof.본 발명은 한련초 추출물, 이의 분획물, 터트티에닐 유도체 또는 이의 약학적으로 허용가능한 염을 포함하는 탈모방지 또는 발모촉진용 조성물에 관한 것이다. 보다 구체적으로, 상기 조성물은 TGF-β의 발현을 현저히 억제시킴으로써, 탈모방지, 육모, 양모, 발모 촉진에 유용히 사용될 수 있으며, 탈모방지용 용액, 크림, 로션, 샴푸, 스프레이, 겔 및 로션 등의 형태로 사용될 수 있다.
