A modulator of NRG1 for treatment of respiratory disorders

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专利权人:

Novartis AG

发明人:

Jackson, Alan,Jones, Carol Elizabeth

申请号：

AU2008292262

公开号：

AU2008292262B2

申请日:

2008.08.22

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention relates to modulators of the Neuregulin (NRG) family,particularly NRG1 and more particularly NRG1β, and most particularlyNRG1β1. The present invention also relates to the use of such modulatorsto inhibit goblet cell hyperplasia and therefore also relates to the use of suchmodulators in the treatment or prevention of human diseases and disorders featuringpathological mucus production such as COPD, CF, chronic bronchitis and asthma.

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