Andy Y. Chang,Travis J. Williams,Emine Boz,CHANG, Andy, Y. ,WILLIAMS, Travis, J. ,BOZ, Emine
申请号：
US13517995
公开号：
US20120277573A1
申请日:
2010.12.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides nanoparticles for delivery of imaging agents, drugs, and other molecules, such as genetic material. The nanoparticles have a core structure comprising the imaging agent and/or drug, and a shell structure that allows for water solubility. The shell structure further provides a barrier with limited water permeability that protects the core. The nanoparticles can be induced to release their cargo by treatment with ultrasound. Methods of delivering drugs and imaging agents are also provided, whereby the nanoparticles are delivered to tissues of interest in a substantially inert form, then activated using ultra-sound to release the drugs or imaging agents.
