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POLYPEPTIDES MULTIMERES MODULATEURS DES LYMPHOCYTES T ET LEURS METHODES D'UTILISATION
专利权人:
CUE BIOPHARMA; INC.
发明人:
SEIDEL, RONALD D., III,CHAPARRO, RODOLFO
申请号:
CA3043630
公开号:
CA3043630A1
申请日:
2017.12.20
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present disclosure provides variant immunomodulatory polypeptides, and fusion polypeptides comprising the variant immunomodulatory peptides. The present disclosure provides T-cell modulatory multimeric polypeptides, and compositions comprising same, where the T-cell modulatory multimeric polypeptides comprise a variant immunomodulatory polypeptide of the present disclosure. The present disclosure provides nucleic acids comprising nucleotide sequences encoding the T-cell modulatory multimeric polypeptides, and host cells comprising the nucleic acids. The present disclosure provides methods of modulating the activity of a T cell; the methods comprise contacting the T cell with a T-cell modulatory multimeric polypeptide of the present disclosure.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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