Nancy Sullivan,Sabue Mulangu,Davide Corti,Antonio Lanzavecchia,Barney Graham,Jean-Jacques Muyembe-Tamfun,John Trefry,Julie Ledgerwood,Daphne Stanley
申请号:
US15526661
公开号:
US10160795B2
申请日:
2015.11.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Neutralizing antibodies and antigen binding fragments that specifically bind to Ebola virus glycoprotein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting Ebola virus using the antibodies and antigen binding fragments are disclosed. The antibodies, antigen binding fragments, nucleic acids, and vectors, can be used, for example, to prevent and/or treat Ebola virus infection in a subject.