Provided herein are single-chain chimeric polypeptides that include: (i) a first target-binding domain； (ii) a soluble tissue factor domain； and (iii) a second target-binding domain. Also provided here are methods of using these single-chain chimeric polypeptides and nucleic acids encoding these single-chain chimeric polypeptides.本文提供單鏈嵌合多肽，其包括：(i)第一標靶結合性結構域；(ii)可溶性組織因子結構域；及(iii)第二標靶結合性結構域。本文亦提供使用此等單鏈嵌合多肽之方法，及編碼此等單鏈嵌合多肽之核酸。
