Jan Torleif Pedersen,Kristian Kjærgaard,Lars Østergaard Pedersen,Abdur-Rasheed Asuni,Nina Helen Rosenqvist,Justus Claus Alfred Daechsel,Karsten Juhl,Lena Tagmose,Mauro Marigo,Thomas Jensen,Søren Chris
申请号：
US15645442
公开号：
US10472415B2
申请日:
2017.07.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
