PROBLEM TO BE SOLVED: To provide a base material or a device effective in inhibiting organ inflammation caused by disorders which are developed or worsened by intervention of cytokines or chemokines, represented by SIRS.SOLUTION: There is provided a base material for inhibiting organ inflammation including a water insoluble carrier and a predetermined vitamin E derivative carried by the water insoluble carrier, and arranged in a blood extracorporeal circulation circuit in a manner of making contact with the blood of the therapeutic object, and there is also provided a device including the base material.COPYRIGHT: (C)2014,JPO&INPIT【課題】SIRSに代表されるサイトカイン・ケモカイン類が介在して発症または悪化する疾患によって生じる、臓器炎症の抑制に有効な基材及びデバイスを提供する。【解決手段】水不溶性担体と、該水不溶性担体に担持された所定のビタミンE誘導体とを備え、血液体外循環回路に、治療対象の血液と接触するように配置される臓器炎症抑制用基材及びこの基材を備えるデバイス。【選択図】なし