ZHANG, QIANG,DAI, WENBING,WANG, JIANCHENG,ZHANG, XUAN
申请号:
EP11821127
公开号:
EP2612655A4
申请日:
2011.08.31
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
A liquid composition of an insoluble medicament and a preparation method thereof are disclosed. The composition includes insoluble medicament, oil for injection, phospholipid, and solvent the percentage by weight of each component is as follows: insoluble medicament 0.01-10%, oil for injection 0%-20%, phospholipid 10-80%, solvent 20-89%. The preparation method for the composition includes the following steps: dissolving an insoluble medicament into solvent or oil for injection or a mixture thereof firstly, and then adding other components, and mixing uniformly or dissolving an insoluble medicament into a mixture of other components, and mixing uniformly or dissolving an insoluble medicament into part of solvent firstly, and then adding into a mixed solvent of other components and the remaining solvent, and mixing uniformly.