Buffering agents for biopharmaceutical formulations

• 收藏
• 分享

专利权人:

Inc.;Amgen

发明人:

Gokarn, Yatin

申请号：

AU2007240732

公开号：

AU2007240732B2

申请日:

2007.04.19

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The invention provides a biopharmaceutical formulation including an aqueous solution having a propionate buffer with a pH from about 4.0 to about 6.0, at least one excipient and an effective amount of a therapeutic polypeptide. The propionate buffer can include a concentration selected from between about 1-50 mM, 2-30 mM, 3-20 mM, 4-10 mM and 5-8 mM. The therapeutic polypeptide included in a biopharmaceutical formulation of the invention can include an antibody, Fd, Fv, Fab, F(ab'), F(ab)

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/