PROBLEM TO BE SOLVED: To provide an effective and safe muscle function reduction inhibitor, muscle atrophy inhibitor, muscle regeneration promoter, and muscle stem cell proliferation agent, which can be used continuously daily.SOLUTION: The invention relates to a muscle function reduction inhibitor containing Euphrasia officinalis extract and, more specifically, to a muscle atrophy inhibitor, a muscle regeneration promoter, and a muscled stem cell proliferation agent, which contain the Euphrasia officinalis extract. As a formulation form, though various types may be selected, an internal agent is particularly preferable. The invention is useful for pharmaceuticals, quasi drugs, foods, and cosmetics aiming at the inhibition of muscle function reduction.