Mortensen, Deborah Sue,Mederos, Maria Mercedes Delgado,Sapienza, John Joseph,Albers, Ronald J.,Lee, Brandon G,Harris, Roy Leonard lll,Shevlin, Graziella Isabel,Huang, Dehua,Schwarz, Kimberley Lyn,Pack
申请号：
ES09006829
公开号：
ES2627352T3
申请日:
2007.10.18
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound with the following formula: ** Formula ** or its pharmaceutically acceptable salt, wherein: R1 is unsubstituted or substituted phenyl with a substituted or unsubstituted C3-10 heteroaryl group； R2 is methyl or ethyl substituted with substituted or unsubstituted heterocycloalkyl； R3 is H, substituted or unsubstituted C1-8 alkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, -NHR4 or -N (R4) 2； and R4 is in each case independently substituted or unsubstituted C1-8 alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted heterocycloalkyl.Un compuesto con la siguiente fórmula:**Fórmula** o su sal farmacéuticamente aceptable, donde: R1 es fenilo no sustituido o sustituido con un grupo heteroarilo C3-10 sustituido o no sustituido； R2 es metilo o etilo sustituido con heterocicloalquilo sustituido o no sustituido； R3 es H, alquilo C1-8 sustituido o no sustituido, heteroarilo sustituido o no sustituido, cicloalquilo sustituido o no sustituido, heterocicloalquilo sustituido o no sustituido, -NHR4 o -N(R4)2； y R4 es en cada caso independientemente alquilo C1-8 sustituido o no sustituido, arilo sustituido o no sustituido, heteroarilo sustituido o no sustituido, cicloalquilo sustituido o no sustituido, o heterocicloalquilo sustituido o no sustituido.
