SOOD ANUP,ROTHMAN JAMES E,LOWERY LISA,BURCZAK JOHN,LIM HAE WON,MOHAN PRAVEENA
申请号：
IN1497/DELNP/2014
公开号：
IN2014DN01497A
申请日:
2014.02.27
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfiuorocarbon gas a therapeutic agent a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
