Sood, Anup,Rothman, James E.,Lowery, Lisa,Burczak, John,Lim, Hae Won,Mohan, Praveena
申请号：
AU2012311659
公开号：
AU2012311659B2
申请日:
2012.09.18
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfiuorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.
