Anti-DR5 antibody and use thereof

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专利权人:

Ltd.;Dong-A ST Co.

发明人:

Doh, Hyounmie,Lee, Dongsop,Lee, Han Young,Kim, Yoojin,Han, Kyungmi,Jung, Eunee,Kim, Donghyeon,Song, Dongsup,Shin, Kum-Joo,Woo, Soyon

申请号：

AU2018239725

公开号：

AU2018239725A1

申请日:

2018.02.08

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present invention relates to an antibody that specifically binds to death receptor 5 (DR5) and has a function of killing cancer cells. Specifically, provided are an anti-DR5 antibody or antigen-binding fragment thereof, and a use of the antibody or antigen-binding fragment for preventing or treating cancer. The present invention is characterized in that the anti-DR5 antibody or antigen-binding fragment thereof is improved in terms of affinity to DR5, stability, and an effect of killing cancer cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/