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Modified Cpn10 and PRR signalling
专利权人:
Jeanette Elizabeth Stok;Kylie Jane Ralston;Christopher Bruce Howard;Christopher John De Bakker;Andrew Leigh James;Richard James Brown;Walter R;Daniel Scott Lambert;Dean Jason Naylor;Linda Alisson Ward
发明人:
Dean Jason Naylor,Richard James Brown,Christopher Bruce Howard,Christopher John De Bakker,Linda Alisson Ward,Jeanette Elizabeth Stok,Andrew Leigh James,Daniel Scott Lambert,Kylie Jane Ralston,Walter R
申请号:
US12934980
公开号:
US09234019B2
申请日:
2009.04.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to isolated Cpn10 polypeptides possessing an increased affinity for a PRR ligand compared to Ala Cpn10 polypeptide. In a further embodiment, the present invention also relates to modified chaperonin 10 polypeptides, and to nucleic acids encoding the same and to compositions comprising such polypeptides and uses thereof.
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