UNIVERSITY HEALTH NETWORK;THE HOSPITAL FOR SICK CHILDREN
发明人:
RAJAKUMAR, SUJEETHA,DANSKA, JAYNE,DICK, JOHN,JIN, LIQING,THEOCHARIDES, ALEXANDRE,WANG, C. Y. JEAN
申请号:
CA2761438
公开号:
CA2761438C
申请日:
2010.05.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to modulating the SIRP.alpha.-CD47 interaction in orderto treat hematological cancer and compoundstherefor. In some embodiments, there is provided methods and uses ofSIRP.alpha. polypeptides, fragments and fusion proteinsfor treating hematological cancer, preferably human acute myeloid leukemia.