Heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators

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专利权人:

Actelion Pharmaceuticals Ltd.

发明人:

Hamed Aissaoui,Christoph Boss,Sylvia Richard-Bildstein,Romain Siegrist

申请号：

US14367823

公开号：

US09255090B2

申请日:

2012.12.20

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to phenyl-substituted heterocyclyl derivatives of the formula (I),wherein Z, n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.

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