WINKEL, JAN VAN DE,PARREN, PAUL,GRAUS, YVO,OPRINS, JUDITH,WEERS, MICHEL DE,BAADSGAARD, OLE,LISBY, STEEN
申请号：
NZ57612207
公开号：
NZ576122A
申请日:
2007.09.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is the use of a non-agonistic antibody which binds CD38 in the manufacture of a medicament for the treatment of a patient with cancer involving CD38 expressing tumor cells, wherein the patient has been pretreated with at least one corticosteroid and at least one non-corticosteroid chemotherapeutic agent. Further disclosed is a method for inhibiting growth and/or proliferation of tumor cells expressing CD38 in a non-human animal in need thereof, which method comprises administration to the said animal of i) a non-agonistic antibody which binds to CD38, ii) at least one corticosteroid, and iii) at least one non-corticosteroid chemotherapeutic agent.
