Shijiazhuang Yiling Pharmaceutical Co., Ltd.;Institute of Mataria Medica, Chinese Academy of Medical Sciences
发明人:
申请号：
EP18832775.3
公开号：
EP3653601A1
申请日:
2018.09.07
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention discloses a type-B crystal form of fenolamine, a preparation method thereof, and a composition and use thereof, more particularly a type-B crystal form of the fenolamine compound (chemical name: trans-2-(2,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenylethyl)acrylamide, a preparation method thereof, and a composition and use thereof. Specifically, the present invention discloses the presence of a solid of a type-B fenolamine crystal form in solid state； a method for preparing the solid of type-B crystal form； and use of the solid of the type-B fenolamine crystal form as a pharmaceutical active ingredient in the manufacture of a medicament for prevention and treatment of Parkinson's disease (PD), improvement of learning and memory disorder, and treatment of memory loss and Alzheimer's disease (AD).
