Общество с ограниченной ответственностью "Кардиотехника" (RU)
发明人:
Байкова Дарья Александровна (RU),Зайцев Иван Леонидович (RU),Поздняков Сергей Евгеньевич (RU),Сёмин Роман Борисович (RU)
申请号：
RU2017144902
公开号：
RU2017144902A
申请日:
2017.12.20
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely to bioprosthesis of heart valves. Valve framework is made from high-strength titanium alloy BT 1–0 or from alloy containing 35 % of cobalt, 35 % of nickel, 20 % of chrome and 10 % of molybdenum. Valve framework has three flexible struts and elastically deformable base and is covered with synthetic fabric. Primary skin of the frame with synthetic fabric is made so that all fixing sutures are located outside the prosthesis. On top of the rack, a wrapping knitting element is made to increase the reliability of fastening the locking element to the frame posts. Inner lining of the frame is completely made of biological tissue representing pericardium of calf or pericardium of pig, so that the through hole of the bioprosthesis is completely covered with biological tissue and has no sutures in the lumen of the valve. Shutter flaps are cut out of xenopericardium after 12–48 hours in neutral 0.3–0.8 % aqueous solution of glutaric aldehyde or in neutral 0.5–5 % water solution of diglycidyl ether of ethylene glycol. Flaps are attached to the frame posts by a double symmetrical mattress suture, wherein the flaps are butt-jointed, and wherein the bioprosthesis closure element is formed after the stabilization process of the xenopericardium biotissue is completed with the cross-linking agent after the bioprosthesis closure element is fixed to the posts and to the base of the frame. Position of the flaps of the bioprosthesis closure element is changed with 6–12-hour periodicity, thereby alternately reproducing the phases of complete opening and complete closure of the flaps of the bioprothesis closure element. Elastic collar of polyester jersey is anchored outside the base of the frame before completion of its internal lining with a biological tissue, but after formation of its closing element.EFFECT: method allows enlarging indications for using this bioprosthesis, implanting into an aortic, mitral and tricu
