COMPOSITION PHARMACEUTIQUE COMPRENANT DES PROTÉINES DE FUSION DESTINÉE À LA PRÉVENTION OU LE TRAITEMENT DE L'HÉPATITE, DE LA FIBROSE HÉPATIQUE ET DE LA CIRRHOSE HÉPATIQUE
HONG, Han Na,KIM, Jun Hwan,CHOI, Hyun Ho,KIM, Dohoon,KIM, Taewang,OH, Se Woong,SONG, Moo Young,KIM, Jong Gyun
申请号：
EP17870009
公开号：
EP3568149A4
申请日:
2017.11.10
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides a composition for preventing or treating hepatitis, hepatic fibrosis, and hepatic cirrhosis. Specifically, the present invention provides a fusion protein comprising a biologically active protein and an FGF21 mutant protein； and a pharmaceutical composition containing the fusion protein, which is effective for preventing or treating hepatitis, hepatic fibrosis, and hepatic cirrhosis. A pharmaceutical composition of the present invention has the effect of inhibiting proliferation of inflammatory cells and fibroblasts, and thus can be effectively used as a composition for preventing or treating hepatitis, hepatic fibrosis, and hepatic cirrhosis.
