There is provided a novel antibody to prevent or to inhibit the proliferation and migration of vascular smooth muscles, vascular hyperplasia and remodeling, and pathological neovascularization of the eye. Furthermore, there is provided a novel antibody that effectively inhibits bronchial hyperplasia and inflammation in asthmatic allergy.Linvention concerne un nouvel anticorps destiné à empêcher ou à inhiber la prolifération et la migration de muscles vasculaires lisses, lhyperplasie vasculaire et le remodelage, ainsi que la néovascularisation pathologique de lœil. En outre, linvention concerne un nouvel anticorps qui inhibe efficacement lhyperplasie bronchique et linflammation dans lallergie asthmatique.