Christine Ambrose,Jeffrey Thompson,Yen-Ming Hsu,Dingyi Wen,Yaping Sun
申请号:
US13645104
公开号:
US08821883B2
申请日:
2012.10.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders.