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compound, prodrug, pharmaceutical agent, and compound use
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
HIROSHI BANNO,KAZUHIRO MIWA,MASAKI SETO,TOMOYASU ISHIKAWA,YOUICHI KAWAKITA
申请号:
BRPI0619911
公开号:
BRPI0619911A2
申请日:
2006.12.01
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by —NR6a—CO—(CH2)n—SO2— optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C1-4 alkyl group, and —(CH2)n— is optionally substituted by C1-4 alkyl, R3a is a hydrogen atom or a C1-6 alkyl group, R4a is a halogen atom or a C1-6 alkyl group, R5a is a halogen atom or a C1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product.
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