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高孔隙度的速崩固體劑型及其包括生產粉末和凍干步驟的製備方法
专利权人:
PANTEC AG
发明人:
KURT HEINZ BAUER
申请号:
HK12112331.9
公开号:
HK1171364B
申请日:
2012.11.29
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The invention relates to a method of manufacture of fast-disintegrating solid dosage forms, characterized in that one or more structure building components in mixed solid powder form are dosed into cavities of blister packs or moulds, the remaining components dissolved in water dosed and added to the powder to form a moistened, plasticized mass, frozen to below −20° C., and the water sublimed in high vacuum. In this way solid dosage forms are obtained with a similar porous structure as usually result from freeze drying processes, but the process requires much less water, which means considerably less time and less energy.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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