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CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS
专利权人:
Grünenthal GmbH
发明人:
Judy Ashworth,Elisabeth Arkenau-Maric,Johannes Bartholomäus,Heinrich Kugelmann
申请号:
US14994691
公开号:
US20160120810A1
申请日:
2016.01.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to a dosage form comprising a physiologically effective amount of a physiologically active substance (A), a synthetic, semi-synthetic or natural polymer (C), optionally one or more physiologically acceptable auxiliary substances (B) and optionally a synthetic, semi-synthetic or natural wax (D), wherein the dosage form exhibits a resistance to crushing of at least 400 N and wherein under physiological conditions the release of the physiologically active substance (A) from the dosage form is at least partially delayed.
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