Elisabeth ARKENAU-MARIC,Johannes BARTHOLOMÄUS,Heinrich KUGELMANN
申请号:
US14141793
公开号:
US20140112984A1
申请日:
2013.12.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to a dosage form comprising a physiologically effective amount of a physiologically active substance (A), a synthetic, semi-synthetic or natural polymer (C), optionally one or more physiologically acceptable auxiliary substances (B) and optionally a synthetic, semi-synthetic or natural wax (D), wherein the dosage form exhibits a resistance to crushing of at least 400 N and wherein under physiological conditions the release of the physiologically active substance (A) from the dosage form is at least partially delayed.