Christian Gieffers,Oliver Hill,Meinolf Thiemann,Tim Schnyder
申请号：
US15957279
公开号：
US10533043B2
申请日:
2018.04.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are specific GITR receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a GITRL-associated disease or disorder. The GITR receptor agonist proteins provided herein comprise three soluble GITRL domains and an Fc fragment. The GITR receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
