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Rapid Melt Controlled Release Taste-Masked Compositions
专利权人:
Subraman Rao Cherukuri
发明人:
Subraman Rao Cherukuri
申请号:
US13589101
公开号:
US20130071476A1
申请日:
2012.08.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Rapid melt tablets that dissolve and release an active component in the oral cavity are comprised of a pharmaceutical active ingredient such as dextromethorphan complexed with a resin that is effective in taste-masking the otherwise bitter taste of the active making it convenient for oral administration. The drug/resin-complexed particles can be coated with water swellable or water insoluble polymers to impart controlled release properties to the active ingredient. A rapid melt tablet also comprises diluents, sweeteners, flavors, disintegrants and other excipients to form granules that can be compressed into tablets at low pressure without the need for a binding agent.
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中国工程科技知识中心
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