CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL USES THEREOF

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专利权人:

ASTRAZENECA AB

发明人:

RONN, Robert,LINDH, Carl, Jonas,RINGBERG, Erik,ANDERSSON, Hanna, Birgitta, Ellinor,NILSSON, Peter,SCHAAL, Wesley, Ralph,MUNCK AF ROSENSCHOLD, Magnus,NIKITIDIS, Antonios,NIKITIDIS, Grigorios,JOHANNESSO

申请号：

PH12017502021

公开号：

PH12017502021A1

申请日:

2017.11.07

申请国别(地区):

PH

年份:

2018

代理人:

摘要：

There is provided compounds of formula (I), wherein E1, E2, E3, E4, L1, Y1, Y2, Y3, Ra and z have meanings provided in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of respiratory diseases and inflammation.

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http://www.ckcest.cn/home/