Robert Ronn,Carl Jonas Lindh,Erik Ringberg,Hanna Birgitta Ellinor Andersson,Peter Nilsson,Wesley Ralph Schaal,Magnus Munck af Rosenschöld,Antonios Nikitidis,Grigorios Nikitidis,Petra Johannesson,Chris
申请号:
US15146152
公开号:
US09657001B2
申请日:
2016.05.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
There is provided compounds of formula I,wherein E1, E2, E3, E4, L1, Y1, Y2, Y3, Ra and z have meanings provided in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of respiratory diseases and inflammation.