Thomas ENGSTRAND,David BERGLUND,Carl PÅLSSON,Folke KNUTSON
申请号:
US16632096
公开号:
US20200164079A1
申请日:
2018.07.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
An active principle for use in prevention or treatment of bacteria-induced infection and disease, wherein the active principle includes a carrier which exhibits a plurality of a scavenger structure which is capable of interacting with bacteria and reducing its growth and/or adhesion to a surface, the scavenger structure including a nucleophilic center complying with the formula X1(—;R″;—;)(—;R′;)mHn (formula I) where a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair, b) m is 0 or 1 and n is 1 or 2, c) —;R″;—; is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence, and d) R′;—; is a monovalent organic group attached to the X1 via its free valence.