An inflation garment for the treatment of DVT is operated by a portable, battery powered air pump and controller detachably mounted on an interface plate incorporated into the inflation garment. The interface plate is formed with outwardly projecting mounting spikes that are engagable with openings in the controller housing to affect a detachable mounting of the housing to the interface plate. The air inlet and discharge receivers on the housing are asymmetrically oriented to promote proper mounting of the controller on the inflation garment. The air inlet and discharge receivers are engagable with inlet and discharge ports in the interface plate. For the multiple chamber inflation garment utilizing the battery powered detachable air pump and controller, the inflation chambers are provided with valves between adjoining chambers that allow sequential pressurizing of the inflation chambers and a simultaneous discharge of air from the chambers to complete a therapy cycle.