A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70%, and has a low degree of polymerization (dp). Other fractions of the extract have minimal polyphenols, fiber, and protein, but contain more than 90% sugars. In some specific examples, the individual extracts are obtained by sequential ultrafiltration of a water extract of the grape seeds. A first ultrafiltration provides a first permeate (Fraction A) enriched in sugars which is useful as a flavorant, and a first retentate. The first retentate is reconstituted and subjected to a second ultrafiltration at a higher molecular weight cutoff to produce a second permeate (Fraction B) that is enriched in low molecular weight polyphenols, and a second retentate (Fraction C) that is enriched in seed fiber. The Fractions are individually suitable for different nutraceutical products, or can be combined with each other in any combination and/or with other nutraceutical agents to enhance vascular and cognitive health.本發明提供一種富含原花青素、總多酚少於70%且具有低聚合度(dp)之新穎葡萄籽萃取物。該萃取物之其他部分具有極少多酚、纖維及蛋白質,但含有多於90%糖。在一些特定實施例中,個別萃取物藉由依序超過濾該等葡萄籽之水萃取物獲得。第一超過濾提供富含糖適用作調味劑之第一滲透物(部分A)及第一保留物。使該第一保留物復原且在較高分子量截斷下經受第二超過濾以產生富含低分子量多酚之第二滲透物(部分B),及富含籽纖維之第二保留物(部分C)。該等部分單獨地適用於不同營養藥劑產品,或可以任何組合彼此組合及/或與其他營養藥劑組合以增強血管及認知健康。