The present invention relates to a liquid drug medical device for use with a syringe having a syringe tip with a distal end with a laterally projecting lip having an external diameter D2, and a medicinal vial with a rubber stopper, the device including an adapter for snap fitting onto the vial and including a hollow puncturing member rigidly connected to the adapter for puncturing the rubber stopper on snap fitting the adapter on the vial, the device further including a short elastomer tubing in flow communication with the puncturing member, and having a distal end with a nominal internal diameter D1<;D2 and of at least 3mm for being sealingly stretched over the syringe's laterally projecting lip for effecting fluid communication between the syringe and the medicinal vial.L'invention concerne des dispositifs médicaux pour médicaments liquides permettant l'administration de médicaments liquides, ainsi qu'un dispositif d'enlèvement de protection d'aiguille permettant d'enlever des protections d'aiguille de manière sûre.