A machine for cold sanification of medical devices includes a sanification chamber adapted to house at least one medical device to be treated, a first delivery system supplying one or more sanification fluids and having a plurality of hydraulic circuits each having a drawing conduit for the sanification fluids connectable to a respective reservoir and a plurality of delivering conduits connected with the sanification chamber for introducing the pressurized fluids therein, a second delivery system fluidically connecting one or more of the drawing conduits with corresponding inner channels of a device housed into the sanification chamber. The first delivery system includes a central collector interposed between the drawing conduits and the delivering conduits, which receive from the first the fluids and supply to each of the delivering conduits the sanification fluids at substantially the same pressure.
