The present invention includes a method of preventing or treating acute lung injury with a MAP3K2/MAP3K3 inhibitor. The present invention further includes compositions useful in the present invention and kits containing the compositions.本発明は、急性肺傷害をMAP3K2/MAP3K3阻害薬を用いて予防または処置する方法を含む。本発明は、本発明において有用な組成物および該組成物を含むキットをさらに含む。