The present invention provides antigen binding molecules comprising: antigen binding domains which have binding affinity to human FcRn under acidic pH conditions and with which the binding affinity of the antigen binding molecules to antigens is altered according to ion concentration conditions； and Fc receptor binding domains which have a higher binding affinity to Fc receptors under neutral pH conditions than the Fc receptor binding domains of the Fc regions of natural human IgG having a fucose containing sugar chain as the sugar chain bound to position 297 (EU numbering).
